Cancer drug points way to new Alzheimer’s approach (Reuters)
Friday, September 3rd, 2010
CHICAGO (Reuters) – An changed edition of the cancer take Gleevec could modify the foundation of a newborn collection of drugs that country the utilization of brain-damaging plaques in Alzheimer’s disease, U.S. researchers said on Wednesday.
They said they hoped drugmakers could mend with the instruction for Gleevec, a preventive that has transformed the communication of digit identify of leukemia, to attain it impact safely in the brain.
The key lies in an enzyme that triggers the creation of beta amyloid plaques, digit of the hallmarks of Alzheimer’s. Gleevec, today utilised to impact habitual myeloid leukemia, blocks this gamma-secretase activity protein.
“Our findings expose that gamma-secretase activity accelerator is a possibleness direct for a newborn collection of anti-amyloid therapies,” said Apostle Greengard, succeeder of the ..read more